NDI CLA (CONJUGATED LINOLEIC ACID) ENYEMAKA ARỌ?

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Ulo Ahụike Ahụ ike Nri Fitness oi-Amritha K Site Amritha K. na Machị 7, 2019

Ihe omume ọha mmadụ banyere oke ọnwụ ahụwo ịrị elu dị ịrịba ama n'oge a. Ma nke ahụ abụghị ihe ọjọọ - na-atụle ọnụ ọgụgụ zuru ụwa ọnụ nke na-ekpughe oke ibu na oke ibu. Nke a kwekọrọ na ịrị elu nke ịchọ ụzọ dị mfe isi belata. E wezụga mmega ahụ na ịnwụ anwụ, ụfọdụ mgbakwunye na-adịkwa maka mbenata ibu ibu. Gụ na ịmatakwu banyere CLA (Conjugated Linoleic Acid), otu n’ime ihe kachasị dị irè na-enyere aka ọnwụ.

akwa akwa akwa akwa akwa

Kedu ihe ejikọtara acid linoleic?

A makwaara dị ka CLA, ọ bụ acid fatty acid dị na ngwaahịa na mmiri ara ehi. Omega-6 fatty acid, ọ bụ ngwaahịa nke mgbaze site na ụmụ nje n'ime afọ mbụ ma ọ bụ asịrị nke anụ ọhịa na-eri ahịhịa dịka ewu, atụrụ, buffalo, ehi. A na-ahụkwa ya na ọkụkọ. A na-agbanwe linoleic acid na CLA site na nje bacteria na-eme nri (Butyrivibrio fibrisolvens) na akụkụ nri nke anụ na-eri ahịhịa. A na-emepụta acid fatty n'ụlọ ọrụ na arụ ọrụ, site na hydrogenation ma ọ bụ ọgwụgwọ okpomọkụ nke linoleic acid ^[1] , ^[abụọ] .

Studiesfọdụ nnyocha na-egosi na ọnụ ọgụgụ CLA dị na anụ na mmiri ara ehi na-adabere na afọ anụmanụ, ụdị, nri ya na ihe ndị ọzọ a na-ahụ maka oge. CLA, mgbe a gbanwere ya na tract digestive, echekwara na anụ ahụ anụ ahụ na mmiri ara ehi.

CLA dị iche iche na ndị a ma ama bụ c9, t11 (cis-9, trans-11) na t10, c12 (trans-10, cis-12). E wezụga na-ewe anụ na mmiri ara ehi na ngwaahịa, ị nwere ike nweta CLA gị usoro site Mmeju (ọgwụ na sirop) ^[3] .

CLA nwere uru dị iche iche, na ọnwụ dị oke mkpa. E wezụga nke ahụ, a na-ekwusi ike na acid iji nyere aka ịlụ ọgụ kansa, na-emeso ụkwara ume ọkụ, meziwanye ahụ mmadụ, belata ọkwa cholesterol, bulie ọgụ, na-achịkwa mmeghachi omume nfụkasị, jikwaa ọrịa shuga na ọbara shuga, na ịlụ ọgụ mbufụt. Ọ bụ ezie na ejikọtara ya na uru ndị ahụ e kwuru na mbụ, ọmụmụ ihe sara mbara elebara anya na mmetụta ọ nwere na mbenata ibu na ire ọkụ ahụ. ^[4] .

Conjugated Linoleic Acid Maka Ibu Loss

CLA na-enye aka n'ibelata ahụ gị site na ibuli ọnụọgụ basal. Fatty acid na - ebute usoro kemịkalụ nke na - akpali usoro abụba n’ahụ gị. Ọ nwere ike ịrụ ọrụ site na ime ka metabolism gị dị ngwa, site na ịbawanye nguzogide insulin gị, site na inyere ahụ gị aka ịchịkọta abụba ahụ yana site na igbu mkpụrụ ndụ abụba ọcha ^[5] .

Dika onu ogugu ihe omumu emere na nghota nke CLA na onwu di egwu, enwere ike ikwuputa na acid fatty na-emetụta oke onwu site na ime ihe banyere PPAR-gamma ndi mmadu iji gbochie ihe nketa nke bu maka nchekwa abụba na adipocyte (abụba) cell) imepụta. Site na nke a, CLA na-enye aka igbochi uru bara ụba - yabụ na-egbochi oke abụba. N'otu aka ahụ, usoro a na-enyere aka n'ịkwalite arụmọrụ nke imeju, na-ebelata oke abụba. Iri CLA na-ebuli ike nke ahụ gị, na-enyere aka na abụba abụba ^[6] , ^[7] .

A na-egosiputa CLA ịbawanye satiety, yabụ na-ahapụ gị ka afọ juru gị. Nke a n'aka na-enyere aka belata agụụ gị na mkpa ị na-eri nri mgbe niile. CLA na-eme site na ịmachi ihe mgbaàmà na-egosi agụụ na-etolite na mpaghara hypothalamus nke ụbụrụ gị.

Nnyocha ọzọ emere na ụmụ nwoke na ụmụ nwanyị 180 buru ibu, na ọnụ ọgụgụ ziri ezi bụ ụmụ nwanyị 149 na ụmụ nwoke 31. A hụrụ otu ahụ maka oge nke ọnwa 12. E kewara otu ahụ na subgroups atọ ma nye ha ọgwụ mgbochi (4.5 gram nke 80% CLA) kwa ụbọchị, usoro sirop (gram 3.6 nke 76% CLA gbanwere na capsule) kwa ụbọchị na capsules placebo jupụtara na mmanụ oliv. karị. Emere ihe omumu a n’enweghi mgbanwe obula n’ime nri ndi mmadu ma obu omume ha kwa ubochi ^[8] .

nri ndị a ga-ezere iji belata abụba afọ

N'oge nlere anya, akọwara na ndị mmadụ riri calorie ole na ole wee mụta ibelata nri ha na-eri. Ozugbo emerechara ọmụmụ ihe ahụ, ekpughere na otu ndị riri mkpụrụ ọgwụ CLA na sirop nwere oke mbenata. Ndị otu riri mkpụrụ ọgwụ CLA nwere oke mmanu 7%, na otu ndị riri syrup CLA nwere 9% abụba abụba. Ma mekwara ka ahụ ike dịkwuo mma ^[9] , ^[10] .

Otú ọ dị, onye ga-aghọta na CLA anaghị ebelata dum ahu arọ ma na-akwụsị abụba mkpụrụ ndụ si na-ibu na-eke ihe abụba na gị ahu - nke n'aka nke na-enyere mbenata ibu ibu. Suppdị nkwụsị nke acid fatty acid na-egbochi mkpa iri nri ma ọ bụ nri mgbe niile, nke na-emekwa ka ị belata ịdị arọ gị ^{iri na otu} . CLA bara ezigbo uru n'ibelata abụba afọ, abụba echekwara n'ime afọ gị.

Otu nnyocha nke Mahadum Wisconsin-Madison duziri kwusiri ike na CLA na-ere abụba mgbe ị na-ehi ụra. Ọbụna mgbe ahụ gị zuru ike, acid fatty acid na-arụ ọrụ n'ime ka iwepu abụba dị ukwuu n'ahụ gị. Studies ekpughewo na CLA-ewe gburugburu 2-3 izu ^[12] na-arụsi ọrụ ike ma na-akwalite ọnwụ.

Na ijikọta CLA na ndụ dị mma bụ azịza kachasị mma maka mbenata abụba. Tinyere ọdịdị ya na-egbochi ya na ike ịmịba abụba, na-etinye acid fatty na nri gị nwere ike inyere gị aka tufuo abụba achọghị. Belata starch na shuga ma tinyekwuo abụba akwukwo nri na protein, yogọt, mkpụrụ osisi na akwụkwọ nri akwụkwọ ndụ ^[13] , ^[14] .

Na-elekwasị anya na usoro kachasị mma nke abụba acid maka ọnwụ ọnwụ, enwere ike ịkọwa na ọtụtụ ọmụmụ nyere ndị sonyere n'etiti gram atọ na anọ kwa ụbọchị. Dị ka ndị na-eme nchọpụta si kwuo, gram atọ ma ọ bụ anọ maka oge nke izu iri na abụọ bụ ego ziri ezi. Otú ọ dị, ọ kachasị mma iji kwurịta dọkịta gị tupu ị tinye CLA n'ime nri gị na njem gị na ọnwụ ^{iri na ise} .

Ọ bụrụ na gị BMI (Isi Mass Index) bụ n'okpuru 18.5, ị ga-eripị CLA dị ka ọ pụrụ ịkpata oké nsogbu na oghom mmetụta. Ọ kachasị mma maka ndị nwere BMI karịa 23 ^[16] .

Lelee BMI gị ebe a .

Nri Akwukwo Linoleic Acid

Dị ka ụmụ mmadụ na-apụghị synthesize CLA, onye nwere na-eri nri na a elu CLA larịị iji nweta ya n'ime gị usoro. E wezụga ibu ọnwụ, ị ga-eri CLA maka ọrụ kwesịrị ekwesị nke ahụ gị ^[17] .

Mmiri ara ehi na ngwaahịa mmiri ara ehi

Milimita 250 nke mmiri ara ehi na-ata nwere miligram 20-30
20 gram nri ehi na-ata nri nwere miligrams 20-30
Mmiri ara ehi 250 millilit nwere miligrams 5.5
Mkpụrụ buttermilk 250 nwere miligrams 5.4
Yugọt 170 dị nwere milligrams 4.8
1 tablespoon bọta nwere milligrams 4.7
1 tablespoon utoojoo ude nwere milligrams 4,6
100 grams cheese cheese nwere 4.5 milligrams
100 gram cheddar gram gram 100 nwere miligrams 4.1
& frac12 iko vanilla ice ude nwere milligrams 3.6

Akwa, azụ na anụ

100 gram nke ahịhịa amị nwere miligram 30
100 gram gram gram nwere gram 5,6
150 g salmon nwere milligrams 0,3
100 gram anụ nwere milligrams 2.7
1 nkochi ime akwa nwere milligrams 0,6
100 gram anụ ezi nwere milligrams 0,4

Ndị ọzọ

1 tablespoon mmanụ aki oyibo nwere milligrams 0,1
1 tablespoon mmanụ sunflower 1 nwere milligrams 0,4 ^[18] .

ngwugwu ihu kacha mma maka otutu

Mmetụta Akụkụ nke Conjugated Linoleic Acid

Dịka ihe ọ bụla bara uru ọzọ, ọbụlagodi CLA nwere ụfọdụ ihe metụtara ya ^[19] , ^{[iri abụọ]} .

Mgbe ụfọdụ, CLA nwere ike ibute mbufụt ma duga na mgbochi insulin.
O nwere ike ibute mkpokọta n'ime imeju.
Ddụbiga mmanya ókè na CLA ga-akpata afọ ọsịsa, afọ mgbu, ọgbụgbọ na bloating.
Ihe sirop nke CLA nwere ike belata ọnụ ọgụgụ HDL 'ezigbo' cholesterol na ahụ gị ma bulie LDL 'ọjọọ' cholesterol.
O nwere ike ime ka ọnya ọbara ọcha, nke nwere ike ịkpalite akwara akwara.
CLA nwere ike ibute ngbanwe n 'ọkwa shuga dị n'ọbara, na-etinye ihe ize ndụ nke ọrịa shuga.
Ọ bụrụ na ị nwere ezinụlọ akụkọ ihe mere eme nke ọrịa obi, zere iri nri mgbakwunye CLA.
C Overụbiga mmanya ókè nke CLA nwere ike imebi ọrụ arịa ọbara gị, na-etinye ihe ize ndụ nke ọrịa obi.

Lelee Nkọwa Akwụkwọ

[1]Lee, K. N., Kritchevsky, D., & Parizaa, M. W. (1994). Conjugated linoleic acid na atherosclerosis na rabbits.Atherosclerosis, 108 (1), 19-25.
[abụọ]Park, Y., Albright, K. J., Liu, W., Storkson, J. M., Cook, M. E., & Pariza, M. W. (1997). Mmetụta nke conjugated linoleic acid na ngwakọta ahụ na ụmụ oke. Lipids, 32 (8), 853-858.
[3]Pariza, M. W., Park, Y., & Cook, M. E. (2001). Ndị na-arụ ọrụ na-arụ ọrụ nke linoleic acid conjugated. Ọganihu na nchọpụta lipid, 40 (4), 283-298.
[4]Banni, S., Heys, S. D., & Wahle, K. W. (2019). Conjugated linoleic acids dị ka ihe oriri na-edozi ahụ: ọmụmụ ihe na vivo na usoro selula. InAdvances na conjugated linoleic acid nyocha (p. 273-288). AOCS na-ekwusara.
[5]den Hartigh, L. J., Gao, Z., Goodspeed, L., Wang, S., Das, A. K., Burant, C. F., ... & Blaser, M. J. (2018). Icemụ oke ibu na-efufu ibu n'ihi trans-10, cis-12 Conjugated Linoleic Acid Supplement or Food Restriction Harbor Distinct Gut Microbiota. Akwụkwọ akụkọ nri, 148 (4), 562-572.
[6]Viladomiu, M., Hontecillas, R., & Bassaganya-Riera, J. (2016). Mgbanwe nke mbufụt na ọgụ site na linoleic acid conjugated jikọtara. European Journal of pharmacology, 785, 87-95.
[7]Kim, J. H., Kim, Y., Kim, Y. J., & Park, Na Na (2016). Conjugated linoleic acid: uru ahụike dị ka ngwa nri na-arụ ọrụ. Nyocha kwa afọ nke sayensị na teknụzụ nri, 7, 221-244.
[8]Norris, L. E., Collene, A. L., Asp, M. L., Hsu, JC, Liu, L. F., Richardson, J. R., ... & Belury, M. A. (2009). N'iji tụnyere linoleic acid conjugated conjine na safflower mmanụ na-edozi ahụ na ụmụ nwanyị postmenopausal buru oke ibu nke nwere ụdị ọrịa shuga nke abụọ. Akwụkwọ akụkọ American nke ọgwụ na-edozi ahụ, 90 (3), 468-476.
[9]Zanini, S. F., Colnago, G. L., Pessotti, B. M. S., Bastos, M. R., Casagrande, F. P., & Lima, V. R. (2015). Isi abụba nke broiler ọkụkọ nri nri na abụba abụọ na isi mmalite na conjugated linoleic acid.
[10]Koba, K., & Yanagita, T. (2014). Uru ahụike nke conjugated linoleic acid (CLA). Nnyocha oke na usoro ọgwụgwọ, 8 (6), e525-e532.
iri na otuPlourde, M., Juu, S., Cunnane, S. C., & Jones, P. J. (2008). Conjugated linoleic acids: gịnị kpatara ọdịiche dị n'etiti ọmụmụ anụmanụ na ụmụ mmadụ? .Nutrition Reviews, 66 (7), 415-421.
[12]Pariza, M. W., Ogige, Y., & Cook, M. (2000). Usoro nke Action of Conjugated Linoleic Acid: Ihe Akaebe na Nkọwapụta (44457) Usoro nke Society maka Ahụike Ahụike na Ahụike, 223 (1), 8-13.
[13]Pariza, M. W. (2004). Ele anya na nchekwa na ịdị ire nke conjugated linoleic acid. Akwụkwọ akụkọ American nke ahụike na-edozi ahụ, 79 (6), 1132S-1136S.
[14]Chin, S. F., Storkson, J. M., Liu, W., Albright, K. J., & Pariza, M. W. (1994). Conjugated linoleic acid (9, 11-na 10, 12-octadecadienoic acid) na emeputa na onu ogugu ma enweghi nkpuru nke enweghi ogwu na-enye acid linoleic. Journal of nutrition, 124 (5), 694-701.
iri na iseWatras, A. C., Buchholz, A. C., Close, R. N., Zhang, Z., & Schoeller, D. A. (2007). Ọrụ nke linoleic acid conjugated na mbenata oke abụba na igbochi uru izu ike. Akwụkwọ akụkọ ụwa banyere oke ibu, 31 (3), 481.
[16]Park, Y., Albright, K. J., Storkson, J. M., Liu, W., & Pariza, M. W. (2007). Conjugated linoleic acid (CLA) na - egbochi mkpokọta abụba na uru bara ụba na ụdị anụmanụ. Journal of food Science, 72 (8), S612-S617.
[17]Fuke, G., & Nornberg, J. L. (2017). Nyocha usoro nyocha banyere ịdị irè nke linoleic acid conjugated na ahụike mmadụ. Nyocha dị oke egwu na sayensị na nri na-edozi ahụ, 57 (1), 1-7.
[18]Vélez, M. A., Perotti, M. C., Hynes, E. R., & Gennaro, A. M. (2019). Mmetụta nke lyophilization na nri liposomes jupụtara na conjugated linoleic acid. Journal of Food Engineering, 240, 199-206.
[19]Lehnen, T. E., da Silva, M. R., Camacho, A., Marcadenti, A., & Lehnen, A. M. (2015). Ntụleghachi na mmetụta nke linoleic fatty acid (CLA) conjugated conjugated body body and energetic metabolism. Magazin nke International Society of Sports Nutrition, 12 (1), 36.
[iri abụọ]Barros, P. A. V. D., Generoso, S. D. V., Andrade, M. E. R., da Gama, M. A. S., Lopes, F. C. F., de Sales e Souza, É. L., ... & Cardoso, V. N. (2017). Mmetụta nke bọta linoleic acid-enriched conjugated mgbe 24 gachara nke ntinye intaneti mucositis. Nutrition na cancer, 69 (1), 168-175.