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L-carnitine bụ amino acid, nke emere na ahụ. Ihe amino acid sitere na ya bu ihe eji emecha. Mkpụrụ ahụ na-arụ ọrụ dị mkpa na mmepụta ume n'ime ahụ gị. Site na ibufe acid bara uru n’ime aru gi na mitochondria, nke n’aka nke ya, nyere aka gbaa abụba ume ma gbanwee ya n’ime ike.
A na-emepụta L-carnitine n'ime ahụ gị, nke sitere na amino acid lysine na methionine. Maka ahụ gị iji mepụta ego achọrọ nke L-carnitine, ị ga-enwerịrị ezigbo vitamin C. Ewezuga nke ahụ, enwere ike nweta L-carnitine pere mpe site na iri nri dịka anụ, mmiri ara ehi, azụ wdg. dịkwa n'ụdị mgbakwunye [1] [abụọ] .
Amino acid bụ usoro carnitine na-arụ ọrụ na-arụ ọrụ nke ọma (aha njirimara maka ebe ammonium quaternary metụtara metabolism na mammals, osisi na ụfọdụ nje bacteria), nke a na-ahụkwa n'ụdị D-carnitine, Acetyl-L-carnitine, Propionyl-L-carnitine, na L-carnitine L-tartrate [3] .
obere kalori pasta Ezi ntụziaka
Uru ahụike nke L-carnitine
1. Na-enyere oke aka
L-carnitine ghọrọ onye ama ama n'oge na-adịbeghị anya site n'ike ya nwere iji nyere aka ọnwụ. Mgbakwunye amino acid na-arụ ọrụ site na ibuga fatty acids n'ime sel gị, nke a ga-akpọ ọkụ n'ime ume. Ọ bụ ezie na enwere esemokwu na ikike nke mgbakwunye iji kwalite ọnwụ, ihe ọmụmụ emere na ndị buru oke ibu kwadoro nkwupụta na L-carnitine na-enyere aka ọnwụ [4] .
2. Mee ka ụbụrụ rụọ ọrụ nke ọma
Studiesfọdụ ọmụmụ egosila na L-carnitine nwere ike inyere aka melite ọrụ ụbụrụ gị. Nke ahụ bụ, ọ nwere ike inye aka gbochie mbelata ọgụgụ isi metụtara afọ, nyere aka melite ikike ịmụ ihe, ma nyere aka weghasị ndalata nke ụbụrụ na-egbochi mmalite nke ọrịa Alzheimer na ọrịa ụbụrụ ndị ọzọ. [5] .
Kedu mkpụrụ osisi dị mma maka akpụkpọ ahụ
3. Na-ejikwa ahụike obi
Ejikọtara L-carnitine na mbenata ọbara mgbali na usoro mkpali metụtara ọrịa obi. Ekwenyela na enwere ikike iji melite ọnọdụ nke ndị mmadụ na-arịa ọrịa obi siri ike, dịka ọrịa obi na-arịa ọrịa obi na ọrịa obi na-adịghị ala ala [6] .
4. Na-akwado arụmọrụ
Nnyocha dịgasị iche egosila uru ndị ahụ, ọ bụ ezie na obere, L-carnitine nwere na imeziwanye egwuregwu egwuregwu mmadụ. N'ihi ihe onwunwe a, L-carnitine bụ aha a na-ahụkarị na mpaghara egwuregwu. O nwere ike inye aka mee ka mgbatị gị dịkwuo elu, mee ka ikuku gị dịkwuo ike, mee ka ike gị dịkwuo mma, belata mgbu ahụ ike ma mụbaa mmepụta ọbara ọbara uhie [3] .
5. Na-achịkwa ọria mamịrị
L-carnitine nwere ike inyere gị aka ijikwa ma belata mgbaàmà nke ọrịa shuga, ọkachasị ụdị ọrịa shuga nke abụọ. Ọ bara uru maka ijikwa ihe ndị dị ize ndụ nke ọnọdụ ahụ, dịka amino acid nwere ike inye aka belata ogo shuga dị n'ọbara [6] .
A na-ekwukwa na ọ bara uru maka ịnye ahụ efe site na mgbu obi, ọrịa akụrụ, hyperthyroidism, ịmụ nwa nwoke, ihe otutu, ntutu isi, autism, obi mgbawa na-ezighi ezi, akwara akwara, ike ọgwụgwụ, ịdị arọ ọmụmụ na ndị ọzọ. Agbanyeghị, enweghi ọmụmụ ihe gbasara itinye n'ọrụ na arụmọrụ nke L-carnitine n'ọtụtụ ọnọdụ [7] .
Mmetụta L-carnitine na-emetụta
Ihe mgbakwunye L-carnitine ma ọ bụ injections, ọ bụ ezie na ọ dị mma maka iji mmadụ mee ihe, nwere ike ịkpata mmetụta dị n'akụkụ ụfọdụ ndị mmadụ. Mentionedfọdụ mmetụta dịkarịsịrị nke amino acid bụ ndị akpọrọ n'okpuru [8] .
- Ọgbụgbọ
- Akpịrị
- Afọ mgbu
- Nrekasi obi
- Afọ ọsịsa
- Ọdịdọ
- Azu azu na mmamịrị, ume na ajirija
Ewezuga nke ahụ, ụmụ nwanyị dị ime na ndị na-enye ara ara kwesịrị izere iri L-carnitine [9] . Oké L-carnitine nwere ike ime ka akụrụ ghara ịda, yana ka njọ nke mgbaàmà nke hypothyroidism. Ọzọkwa, zere iwere L-carnitine maka ijikwa ọdịdọ, ọ bụrụ na ịnweelarị njide.
Ọgwụ nke L-carnitine
Mara: You ga-agakwuru onye dọkịta tupu ịtinye mgbakwunye ma ọ bụ injections L-carnitine.
otu esi ebelata ntụpọ ihu n'otu ụbọchị
Dosdị usoro e kwuru ebe a bụ maka ndị okenye [10] .
Enweghi ike L-carnitine: 990 mg, ugboro abụọ ma ọ bụ ugboro atọ kwa ụbọchị (mbadamba ma ọ bụ ọgwụgwọ ọnụ).
Obi mgbu: 900 mg na 2 g na 1 ka 2 kewara doses kwa ụbọchị maka izu 2 ruo ọnwa 6.
Dosedị nke L-carnitine bụ 500-2,000 mg kwa ụbọchị.
ntutu isi maka ntutu isi
Na Achọpụta Ikpeazụ ....
Maka ndị anaghị eri anụ, ịmepụta yana inweta L-carnitine nwere ike ọ gaghị ekwe omume n'ihi enweghị anụ na azụ. Otu ihe a na-emekwa ndị mmadụ na-arịa ụfọdụ mkpụrụ ndụ ihe nketa. Otú ọ dị, mmadụ nwere ike inweta ego achọrọ nke L-carnitine site na iri ihe mgbakwunye L-carnitine.
Lelee Nkọwa Akwụkwọ- [1]Udo, R., Riede, L., Lugo, J., & Bellamine, A. (2018). l-Carnitine supplementation na mgbake mgbe emega ahụ. ndị na-edozi ahụ, 10 (3), 349.
- [abụọ]Koeth, R. A., Lam-Galvez, B. R., Kirsop, J., Wang, Z., Levison, B. S., Gu, X., ... & Culley, M. K. (2018). l-Carnitine na nri niile na-eme ka mmadụ nwee ụzọ atherogenic gut. Akwụkwọ nke Clinical Investigation, 129 (1), 373-387.
- [3]Novakova, K., Kummer, O., Bouitbir, J., Stoffel, S. D., Hoerler-Koerner, U., Bodmer, M., ... & Krähenbühl, S. (2016). Mmetụta nke mgbakwunye l-carnitine na ọdọ mmiri carnitine, ahụ ike skeletal ike metabolism na arụmọrụ anụ ahụ na ndị nwoke anaghị eri anụ. Akwụkwọ akụkọ European oriri na-edozi, 55 (1), 207-217.
- [4]Lee, B. J., Lin, J. S., Lin, Y. C., & Lin, P. T. (2015) Ekpere emi ekekerede. Mmetụta mgbochi nke L-carnitine supplementation (1000 mg / d) na ọrịa ndị na-arịa ọrịa akwara ọbara. Nutrition, 31 (3), 475-479.
- [5]Chan, Y. L., Saad, S., Al-Odat, I., Oliver, B. G., Pollock, C., Jones, N. M., & Chen, H. (2017). Ihe mgbakwunye L-carnitine nke nne na-eme ka ahụike ụbụrụ dị na ụmụ sitere na anwụrụ ọkụ sịga na-ekpughere ndị nne. N'ihu na neuroscience molekụla, 10, 33.
- [6]Fukami, K., Yamagishi, S. I., Sakai, K., Kaida, Y., Yokoro, M., Ueda, S., ... & Okuda, S. (2015). Oral L-carnitine supplementation na-abawanye trimethylamine-N-oxide ma na-ebelata akara nke mmerụ ahụ na-agwọ ọrịa na ndị ọrịa hemodialysis. Akwụkwọ akụkọ nke ọgwụ gbasara mkpụrụ obi, 65 (3), 289-295.
- [7]da Silva, G. S., de Souza, C. W., da Silva, L., Maciel, G., Huguenin, A. B., de Carvalho, M., ... & Colafranceschi, A. (2017). Mmetụta nke L-Carnitine Mgbakwunye na Ntugharị Na-agbanweghachi na Ndị Ọrịa Na-arịa Ọrịa Ischemic Na-arịa Ọrịa Na-akpata Ọrịa Na-akpata Ọkpụkpụ: A Na-enwe Ọrịa, Ọnọdụ Na-achịkwa Ọnọdụ. Annals of nutrition & metabolism, 70 (2), 106.
- [8]Lee, B. J., Lin, J. S., Lin, Y. C., & Lin, P. T. (2016) Ekpere emi ekekerede Mmetụta nke mgbakwunye L-carnitine na profaịlụ lipid na ndị ọrịa nwere ọrịa akwara obi.Lipids na ahụike na ọrịa, 15 (1), 107.
- [9]Pala, R., Genc, E., Tuzcu, M., Orhan, C., Sahin, N., Er, B., ... & Sahin, K. (2018). Ihe mgbakwunye L-Carnitine na-abawanye ngosipụta nke PPAR-γ na ndị na-ebugharị glucose na akwara skelet nke oke na-arụ ọrụ nke ọma. Cellular na molekụla ihe ọmụmụ (Noisy-le-Grand, France), 64 (1), 1-6.
- [10]Imbe, A., Tanimoto, K., Inaba, Y., Sakai, S., Shishikura, K., Imbe, H., ... & Hanafusa, T. (2018). Mmetụta nke mgbakwunye L-carnitine na ndụ nke ndị ọrịa na-arịa ọrịa shuga nke nwere nkwarụ akwara.Endocrine journal, EJ17-0431.
